The demand for cleaner and stable capsules is reshaping the pharmaceutical and Nutraceutical industries. Plant-based alternatives, especially Hydroxypropyl Methylcellulose aka HPMC capsules, are gaining more traction for their improved performance.
ACG stands out as a worldwide leader in HPMC capsule innovation. But what makes ACG’s HPMC capsules a stand-out? And the high-performance choice? Let’s see how it is engineered for higher performance.
What Is HPMC, and Why Is It Disrupting Traditional Capsule Markets?
Gelatin capsules were a go-to standard when it comes to pharmaceutical and nutraceutical delivery. In today’s market, plant-based and clean-label products are reshaping the industry. And of course, HPMC is making a new revolution.
So what exactly is HPMC? And why are they becoming the capsule choice for forward-thinking brands?
What Is HPMC?
The term HPMC stands for Hydroxypropyl Methylcellulose, which is a semi-synthetic, plant-derived polymer formed by chemically modifying cellulose from spruce, pine, and a few more trees.
And in capsule manufacturing, HPMC is the main ingredient to form a vegetarian, non-animal-based shell that can usually deliver solid-dose medications or supplements, which is effective as gelatin, with multiple important advantages.
Particularly, ACG’s HPMC capsules are a hundred percent plant-based and a non-GMO alternative to gelatins that are animal-derived. They are halal, and they favor clean-label. In the nutraceutical sector, they are kosher-certified products. And a key factor is that these capsules work under pressure.
The thought of modern consumers has changed to thinking about what’s inside the capsule shell. That’s where the HPMC capsules are praised a lot:
They are Vegan Friendly:
No animals are harmed or used during the process of making these capsules, which makes their capsules ideal for religious dietary.
Clean-Label Compliant:
They are Non-GMO and Allergen-free in nature, and they align with the clean-label to gain global traction.
Globally Certifiable:
HPMC capsules meet the global compliance needs, which starts from the FDA to satisfying APAC Regulatory standards.
Why HPMC Is Improving the Market?
1. Superior Stability
Gelatin capsules are moisture sensitive and can handle a sticky environment depending on the humidity. And HPMC capsules are stable under a wide range of environmental climates (ICH Zones 3 and 4)
Even without refrigeration, HPMC provides a formulation for probiotics, enzymes, or even for the herbal extracts.
2. Compatibility with Challenging Formulations
Active ingredients in common interact poorly with gelatin, which is a leading issue in crosslinking. This leads to slow dissolution, but HPMC, on the other hand, is chemically inert, as it offers better compatibility as it carries pH-sensitive ingredients, Hygroscopic APIs, and modified-release systems.
3. Delayed and Targeted Release Possibilities
These HPMC Capsules have an ardent pH resistance, which also means they have moisture control. HPMC is used in delayed-release capsules, which are unique for protecting sensitive drugs from stomach acid.
4. Improved Machine Performance
The Modern HPMC capsules are from manufacturers like ACG, who are advanced and offer exceptional dimensional control, which enables high-speed filling and low rejection rates.
Why ACG Is Leading the Charge with HPMC
It is no doubt that ACG is leading a lucrative change in the HPMC capsules. ACG, being one of the world’s trusted capsule manufacturers, ACG offers HPMC capsules beyond the basics:
They are made from sourced cellulose.
They are manufactured in WEF Global Lighthouse facilities.
They are used for long supply chains and for distribution on a global basis.
Starting with formulation to final packaging, ACG provides a vertically integrated solution that is widely trusted by pharma majors across 138 countries.
HPMC capsules are implemented to lead the momentum of solid dosage delivery, even if the formulation challenges grow more in number and when the ethical sourcing becomes a herculean task.